Job Description
Who We Are For more than two decades, going our own way has led to countless breakthroughs, bettering the lives of those suffering from rare genetic disease. In 1997 we were founded to make a big difference in small patient populations. Now we seek to make an even greater impact by applying the same science-driven, patient-forward approach that propelled our last 25 years of drug development to larger genetic disorders, as well as genetic subsets of more common conditions. Through our unparalleled expertise in genetics and molecular biology, we will continue to develop targeted therapies that address the root cause of the conditions we seek to treat. Applying our knowledge to make a transformative impact is not just a calling, but an obligation to those who will benefit most. The end goal has always been better lives and now we can reach more. And the more people we reach, the more our impact can grow. We transform lives through genetic discovery. BioMarin\u2019s Research & Development group is responsible for everything from research and discovery to post-market clinical development. Research & Development involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class or best-in-class therapeutics that provide meaningful advances to patients. Come join our team and make a meaningful impact on patients\u2019 lives. The Neuroscience Therapeutic Area within Research is seeking a motivated and organized Sr. Research Associate to join a highly productive in vivo team. The successful candidate will have experience with animal handling, very good surgical hands, impressive injection skills, abide by welfare regulations, prize accuracy, and must be prepared to contribute individually as well as provide support for other members of the team. The goal is to drive the advancement of the early-stage pipeline with quality data.Responsibilities include: Assist with scheduling and the coordination of in vivo studies across neuroscience portfolio Assist with the design and execution of in vivo model systems and proof of concept studies to understand mechanisms Perform in vivo lab experiments including but not limited to dosing (IV, ICV, IP, Nasal delivery, ICM, etc.), PK/PD studies. Organize and maintain mouse colonies, genotyping, breeding, and standard husbandry Must recognize and adhere to IACUC standards of in vivo research, assist with bookkeeping of protocols, animal usage, document all experiments in electronic notebook, and track registries \u2013 Someone tech savvy that can streamline software communication across functional areas and program workable templates would be desired Engage with project teams, senior members, and cross functional players in a collaborative manner. Learn from and assist in setup and completion of experiments Manage and coordinate pre and post-in vivo study activities including drug receipt and drug storage to tissue sample processing and distribution. Other duties as assignedRequirements: In vivo surgical and injection experience in rodentsBasic understanding of neuroscience and drug applications to neurological and developmental disorders, particularly genetic disorders Basic knowledge of and hands-on experience with rodent in vivo and ex vivo models of developmental biology and neuroscience is highly preferred In vivo, in-life, surgical experience Must work collaboratively and be agile in a dynamic and ever-changing environmentStrong organizational and time-management skills Computer savvy and ability to manage electronic registriesExcellent oral and written English communication skillsAbility to be agile in a fast paced environmentEducation/ExperienceBachelor\u2019s degree and at least 6 years of experience; Master\u2019s degree with at least 4 years of relevant experience Persons without in vivo experience need not apply. PLEASE NOTE: Absent a Medical or Religious reason that prohibits vaccinations, all our incoming employees must be vaccinated for COVID-19. We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity, sexual orientation, national origin, disability status, protected veteran status, or any other characteristic protected by law.
